COMPREHENSIVE GUIDE · 7 ARTICLES
GLP-1 & Weight Management Guide
Semaglutide, tirzepatide, retatrutide, and the next generation of incretin therapies — how they work, how they are dosed, side effects, and what to expect.
TOPICS IN THIS GUIDE
01
How GLP-1 medications work
Receptors, appetite, gastric emptying, and why the dose escalates.
1 article
02
The compounds compared
Semaglutide, tirzepatide, retatrutide, and the pipeline, side by side.
2 articles
- Semaglutide vs. Tirzepatide vs. Retatrutide — The GLP-1 Compounds ComparedSemaglutide, tirzepatide, and retatrutide compared — receptors, trial weight loss, dosing, side effects, availability, and how a provider chooses.2 min read
- Retatrutide Explained — The Triple Agonist, Its Trial Data, and How It Is DosedWhat retatrutide is, why three receptors matter, the phase 2 results, how it is escalated, and what to expect — the compound G1 prescribes.3 min read
03
Dosing & titration
Schedules, reconstitution, missed doses, and plateaus.
2 articles
- GLP-1 Dosing and Titration — Schedules, Reconstitution, and Reading the SyringeEscalation schedules for semaglutide, tirzepatide, and retatrutide, reconstituting compounded vials, and converting a mg dose to syringe units.3 min read
- Missed Doses, Plateaus, and Stopping — GLP-1 Questions After the First MonthsWhat to do when you miss a weekly injection, why weight loss plateaus and what to do about it, and how stopping or tapering GLP-1 medication works.2 min read
04
Side effects & managing them
Nausea, constipation, muscle loss, and the questions to ask your provider.
2 articles
- Managing GLP-1 Side Effects — Nausea, Constipation, Reflux, and FatigueProvider-backed ways to reduce nausea, constipation, reflux, and fatigue on GLP-1 medications, what is normal, and the symptoms that need a call.3 min read
- Preserving Muscle on GLP-1 Medications — Protein, Training, and What the Trials ShowHow much lean mass is lost on semaglutide and tirzepatide, why it matters, and the evidence-based ways to keep muscle while losing fat.3 min read