METABOLIC · PEPTIDE
What is AOD-9604?
Medically reviewed by the G1 Peptides clinical team · Updated October 1, 2026
THE SHORT ANSWER
AOD-9604 is a synthetic fragment of human growth hormone, the part of the molecule linked to fat metabolism. It was developed as an obesity drug and is studied for fat loss without the growth-promoting effects of full growth hormone.
AOD-9604 at a glance
- Type
- Peptide
- Also known as
- hGH fragment 176-191, Anti-Obesity Drug 9604
- Mechanism
- hGH fragment 176–191; lipolytic signalling without growth effects
- Status
- Compounded (Rx)
- Half-life
- Short (limited human data)
- Route
- Subcutaneous
- Dosing range in the literature
- 250–600 mcg daily
- Onset
- 4–8 weeks
- Storage
- Refrigerated (2–8 °C); use within the pharmacy beyond-use date
How AOD-9604 works
It is a modified copy of the tail end of the growth hormone molecule. In laboratory studies it stimulates the breakdown of fat and inhibits the formation of new fat, without raising IGF-1 or affecting blood sugar the way growth hormone does.
What AOD-9604 is studied for
- Fat metabolism
- Body composition
Early trials suggested modest weight loss, but a larger phase 2b trial did not show a meaningful benefit over placebo, and development as an obesity drug stopped. It was well tolerated in those trials.
Being studied for something is not proof that it works. Results in individuals vary.
AOD-9604 dosing
Published protocols describe 250–600 mcg daily, once daily, morning fasted, given subcutaneous. Onset is typically reported at 4–8 weeks.
These figures are context from the literature, not instructions. A licensed provider sets the dose and schedule for each patient.
AOD-9604 side effects and risks
- Injection-site reactions
- Headache
Tell your provider about every medication and condition before starting, and report anything unexpected. See peptide side effects and safety and who should not use peptides.
Is AOD-9604 FDA approved?
Not FDA-approved as a drug.
Approval and trial status change. This page was last reviewed on October 1, 2026.
AOD-9604 at G1 Peptides
G1 Peptides supplies AOD-9604 as vials (5 mg, 10 mg) and in pens (TesaTrim, Lean Recovery, Opti-Lean). Prescription products ship only after a licensed provider has reviewed the order.
AOD-9604 questions
- What is AOD-9604?
- AOD-9604 is a synthetic fragment of human growth hormone, the part of the molecule linked to fat metabolism. It was developed as an obesity drug and is studied for fat loss without the growth-promoting effects of full growth hormone.
- What is AOD-9604 used for?
- AOD-9604 is studied for fat metabolism and body composition. Early trials suggested modest weight loss, but a larger phase 2b trial did not show a meaningful benefit over placebo, and development as an obesity drug stopped. It was well tolerated in those trials.
- How does AOD-9604 work?
- It is a modified copy of the tail end of the growth hormone molecule. In laboratory studies it stimulates the breakdown of fat and inhibits the formation of new fat, without raising IGF-1 or affecting blood sugar the way growth hormone does.
- Is AOD-9604 FDA approved?
- Not FDA-approved as a drug.
- What is the typical AOD-9604 dosage?
- Published protocols describe 250–600 mcg daily, given subcutaneous. This is context from the literature, not a recommendation: a licensed provider sets the dose.
- What are the side effects of AOD-9604?
- Risks noted for AOD-9604 include injection-site reactions and headache. Tell your provider about your medications and conditions before starting.
- What is the half-life of AOD-9604?
- The reported half-life is short (limited human data). Onset is typically reported at 4–8 weeks.
- How should AOD-9604 be stored?
- Refrigerated (2–8 °C); use within the pharmacy beyond-use date.
For educational purposes only, and not medical advice. These statements have not been evaluated by the FDA. Nothing on this page is intended to diagnose, treat, cure, or prevent any disease. Use any compound only under the guidance of a licensed provider.