METABOLIC · COENZYME
What is NAD+?
Medically reviewed by the G1 Peptides clinical team · Updated October 1, 2026
THE SHORT ANSWER
NAD+ is a coenzyme found in every cell, essential for turning food into energy and for repairing DNA. It is not a peptide. Its level falls with age, and it is given by injection or infusion with the aim of restoring it.
NAD+ at a glance
- Type
- Coenzyme
- Also known as
- Nicotinamide adenine dinucleotide, NAD
- Mechanism
- Nicotinamide adenine dinucleotide repletion
- Status
- Compounded (Rx)
- Half-life
- Limited human data
- Route
- Subcutaneous (IV in clinic)
- Dosing range in the literature
- 50–500 mg per dose
- Onset
- Days to weeks
- Storage
- Refrigerated (2–8 °C); use within the pharmacy beyond-use date
How NAD+ works
It carries electrons in the reactions that produce cellular energy, and it is consumed by enzymes that repair DNA and regulate aging-related pathways.
What NAD+ is studied for
- Cellular energy
- Recovery
- Healthy aging
Oral precursors such as NR and NMN raise NAD+ levels in human trials, with modest effects on health measures so far. Evidence for injected or infused NAD+ is limited.
Being studied for something is not proof that it works. Results in individuals vary.
NAD+ dosing
Published protocols describe 50–500 mg per dose, 1–3× weekly (titrated), given subcutaneous (iv in clinic). Onset is typically reported at days to weeks.
These figures are context from the literature, not instructions. A licensed provider sets the dose and schedule for each patient.
NAD+ side effects and risks
- Flushing
- Nausea
- Injection-site discomfort
Tell your provider about every medication and condition before starting, and report anything unexpected. See peptide side effects and safety and who should not use peptides.
Is NAD+ FDA approved?
Not FDA-approved as a drug for these uses.
Approval and trial status change. This page was last reviewed on October 1, 2026.
NAD+ at G1 Peptides
G1 Peptides supplies NAD+ as vials (500 mg, 1,000 mg) and in pens (X-23). Prescription products ship only after a licensed provider has reviewed the order.
NAD+ questions
- What is NAD+?
- NAD+ is a coenzyme found in every cell, essential for turning food into energy and for repairing DNA. It is not a peptide. Its level falls with age, and it is given by injection or infusion with the aim of restoring it.
- What is NAD+ used for?
- NAD+ is studied for cellular energy, recovery, and healthy aging. Oral precursors such as NR and NMN raise NAD+ levels in human trials, with modest effects on health measures so far. Evidence for injected or infused NAD+ is limited.
- How does NAD+ work?
- It carries electrons in the reactions that produce cellular energy, and it is consumed by enzymes that repair DNA and regulate aging-related pathways.
- Is NAD+ FDA approved?
- Not FDA-approved as a drug for these uses.
- What is the typical NAD+ dosage?
- Published protocols describe 50–500 mg per dose, given subcutaneous (iv in clinic). This is context from the literature, not a recommendation: a licensed provider sets the dose.
- What are the side effects of NAD+?
- Risks noted for NAD+ include flushing, nausea, and injection-site discomfort. Tell your provider about your medications and conditions before starting.
- What is the half-life of NAD+?
- The reported half-life is limited human data. Onset is typically reported at days to weeks.
- How should NAD+ be stored?
- Refrigerated (2–8 °C); use within the pharmacy beyond-use date.
For educational purposes only, and not medical advice. These statements have not been evaluated by the FDA. Nothing on this page is intended to diagnose, treat, cure, or prevent any disease. Use any compound only under the guidance of a licensed provider.