What is the typical Ipamorelin dosage?

Published protocols describe 100–300 mcg per dose, given subcutaneous. This is context from the literature, not a recommendation: a licensed provider sets the dose.

What are the side effects of Ipamorelin?

Risks noted for Ipamorelin include headache, water retention, and injection-site reactions. Tell your provider about your medications and conditions before starting.

What is the half-life of Ipamorelin?

The reported half-life is ~2 hours. Onset is typically reported at 1–2 weeks (sleep); 6–12 weeks (composition).

How should Ipamorelin be stored?

Refrigerated (2–8 °C); use within the pharmacy beyond-use date.

GROWTH · PEPTIDE

What is Ipamorelin?

Medically reviewed by the G1 Peptides clinical team · Updated October 1, 2026

THE SHORT ANSWER

Ipamorelin is a synthetic peptide of five amino acids that stimulates the pituitary gland to release growth hormone. It acts on the ghrelin receptor and is described as selective because it has little effect on cortisol or prolactin.

Ipamorelin at a glance

Type: Peptide
Also known as: NNC 26-0161
Mechanism: Selective GH secretagogue (ghrelin receptor agonist)
Status: Compounded (Rx)
Half-life: ~2 hours
Route: Subcutaneous
Dosing range in the literature: 100–300 mcg per dose
Onset: 1–2 weeks (sleep); 6–12 weeks (composition)
Storage: Refrigerated (2–8 °C); use within the pharmacy beyond-use date

How Ipamorelin works

It binds the growth hormone secretagogue receptor, the same receptor as the hunger hormone ghrelin. That triggers a pulse of growth hormone release. Unlike older peptides in its class it does not markedly increase appetite or stress hormones.

What Ipamorelin is studied for

Growth hormone release
Sleep quality
Recovery

Human studies confirm that it raises growth hormone. It was tested for recovery of gut function after surgery without clear benefit, and it has not been approved for any use.

Being studied for something is not proof that it works. Results in individuals vary.

Ipamorelin dosing

Published protocols describe 100–300 mcg per dose, 1–3× daily, given subcutaneous. Onset is typically reported at 1–2 weeks (sleep); 6–12 weeks (composition).

These figures are context from the literature, not instructions. A licensed provider sets the dose and schedule for each patient.

Ipamorelin dosage calculator →

Ipamorelin side effects and risks

Headache
Water retention
Injection-site reactions

Tell your provider about every medication and condition before starting, and report anything unexpected. See peptide side effects and safety and who should not use peptides.

Is Ipamorelin FDA approved?

Not FDA-approved.

Approval and trial status change. This page was last reviewed on October 1, 2026.

Ipamorelin at G1 Peptides

G1 Peptides supplies Ipamorelin as vials (5 mg, 10 mg) and in pens (Apex, Apex Plus, Trinity Stack, Eros X, Fragment Apex, Lean Recovery). Prescription products ship only after a licensed provider has reviewed the order.

Shop Ipamorelin →

Ipamorelin questions

What is Ipamorelin?: Ipamorelin is a synthetic peptide of five amino acids that stimulates the pituitary gland to release growth hormone. It acts on the ghrelin receptor and is described as selective because it has little effect on cortisol or prolactin.
What is Ipamorelin used for?: Ipamorelin is studied for growth hormone release, sleep quality, and recovery. Human studies confirm that it raises growth hormone. It was tested for recovery of gut function after surgery without clear benefit, and it has not been approved for any use.
How does Ipamorelin work?: It binds the growth hormone secretagogue receptor, the same receptor as the hunger hormone ghrelin. That triggers a pulse of growth hormone release. Unlike older peptides in its class it does not markedly increase appetite or stress hormones.
Is Ipamorelin FDA approved?: Not FDA-approved.
What is the typical Ipamorelin dosage?: Published protocols describe 100–300 mcg per dose, given subcutaneous. This is context from the literature, not a recommendation: a licensed provider sets the dose.
What are the side effects of Ipamorelin?: Risks noted for Ipamorelin include headache, water retention, and injection-site reactions. Tell your provider about your medications and conditions before starting.
What is the half-life of Ipamorelin?: The reported half-life is ~2 hours. Onset is typically reported at 1–2 weeks (sleep); 6–12 weeks (composition).
How should Ipamorelin be stored?: Refrigerated (2–8 °C); use within the pharmacy beyond-use date.

For educational purposes only, and not medical advice. These statements have not been evaluated by the FDA. Nothing on this page is intended to diagnose, treat, cure, or prevent any disease. Use any compound only under the guidance of a licensed provider.