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G1 Peptides

COMPARISON TOOL

Sermorelin vs CJC-1295/Ipamorelin vs Tesamorelin

All four prompt your own pituitary to release growth hormone; they differ in which receptor they hit, how hard, and how much evidence stands behind them.

SermorelinCJC-1295 + IpamorelinIpamorelinTesamorelin
Max 4 peptides
PropertySermorelinCJC-1295 + IpamorelinIpamorelinTesamorelin
CategoryGrowthGrowthGrowthGrowth
TypePeptidePeptide blendPeptidePeptide
MechanismGHRH (1–29) analogGHRH analog + selective GHRP (two-receptor GH pulse)Selective GH secretagogue (ghrelin receptor agonist)Stabilized GHRH analog
StatusCompounded (Rx)Compounded (Rx)Compounded (Rx)FDA-approved
Dosing range200–500 mcg nightly200–600 mcg total per dose100–300 mcg per dose1–2 mg daily
FrequencyOnce nightlyOnce nightly (up to 3× daily)1–3× dailyOnce daily
Half-life~10–20 minutes~30 min (CJC) / ~2 h (ipamorelin)~2 hours~26–38 minutes
RouteSubcutaneousSubcutaneousSubcutaneousSubcutaneous
Onset1–2 weeks (sleep); 6–12 weeks (composition)1–2 weeks (sleep); 6–12 weeks (composition)1–2 weeks (sleep); 6–12 weeks (composition)8–12 weeks (visceral fat)
Studied for
  • Growth hormone release
  • Sleep quality
  • Gentle starting point
  • Growth hormone release
  • Sleep quality
  • Recovery
  • Body composition
  • Growth hormone release
  • Sleep quality
  • Recovery
  • Visceral fat reduction
  • Triglycerides
  • Growth hormone release
Key risks
  • Flushing
  • Headache
  • Injection-site reactions
  • Water retention
  • Tingling
  • Headache
  • Headache
  • Water retention
  • Injection-site reactions
  • Joint pain
  • Swelling
  • Glucose increase
  • Injection-site reactions
StorageRefrigerated (2–8 °C); use within the pharmacy beyond-use dateRefrigerated (2–8 °C); use within the pharmacy beyond-use dateRefrigerated (2–8 °C); use within the pharmacy beyond-use dateRefrigerated (2–8 °C); use within the pharmacy beyond-use date
Available at G1Vials: 10 mg, 20 mgPens: Trinity Stack, Wolverine-SShop →Vials: 5/5 mg, 10/10 mgPens: Apex, Apex Plus, Trinity Stack, Fragment Apex, Lean RecoveryShop →Vials: 5 mg, 10 mgPens: Apex, Apex Plus, Trinity Stack, Eros X, Fragment Apex, Lean RecoveryShop →Vials: 10 mgPens: Fragment Apex, TesaTrimShop →
ToolsDosage calculator →Dosage calculator →Dosage calculator →Dosage calculator →

PROPERTY COMPARISON · RADAR

Profile shape

DurationQuick OnsetVersatilityTolerabilityUse CasesStackability
Editorial profile scores (0–10) for orientation — not clinical measurements.

TYPICAL DOSE RANGES

Dose envelope

Sermorelin200 mcg – 500 mcg
CJC-1295 + Ipamorelin200 mcg – 600 mcg
Ipamorelin100 mcg – 300 mcg
Tesamorelin1 mg – 2 mg

Typical per-dose range on a logarithmic scale. Your provider sets your dose.

For educational purposes only. Consult a licensed provider before starting any peptide protocol.